Evidence of Scale-Free Topology in Gene Regulatory Network of Human Tissues

Andrecut, M., Madni, A.M., Este, R.A., and Kauffman, S.A.

Abstract

We report the reconstruction of the topology of gene regulatory network in human tissues. The results show that the connectivity of the regulatory gene network is characterized by a scale-free distribution. This result supports the hypothesis that scale-free networks may represent the common blueprint for gene regulatory networks.

From: Andrecut, M., Madni, A.M., Este, R.A., and Kauffman, S.A., International Journal of Modern Physics C, Vol. 19, Issue 02, pp. 283-290, 2008.